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Jardiance (Empagliflozin): A News Drug for Chronic Kidney Disease

February 16, 2024

Context:

Recently, CDSCO has approved Boehringer Ingelheim’s anti-diabetic drug for the treatment of Chronic kidney disease in India.

Central Drugs Standard Control Organization (CDSCO)

It is the National Regulatory Authority (NRA) of India regulates the quality, safety, and efficacy of drugs including vaccines & the medical devices industry.
Regulation: Drugs & Cosmetics Act 1940 & New Drugs and Clinical Trials Rules, 2019.
Nodal Ministry: Ministry of Health & Family Welfare.
Headed by: Drugs Controller General of India (DCGI)
Headquarters: New Delhi.

What Is Chronic Kidney Disease (CKD)?

It means when kidneys are damaged and can’t filter blood the way they should.
Main Risk factors: Diabetes, High Blood Pressure, Heart disease, and a family history of kidney failure.
CKD Burden in India: An estimated 33 million adults live with CKD in India.

About Jardiance Drug Efficacy

Reduce the risk of sustained decline in estimated glomerular filtration rate (eGFR) which is done to check how well the kidneys are filtering, and end-stage kidney disease.
Reduce Cardiovascular death (Earlier, it was approved only for the treatment of heart failure.)
Reduce Hospitalization of Adults with CKD.

Also Read: Casgevy And Lyfgenia: CRISPR-Based Gene Therapies

News Source: Live Mint

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