Context
Twenty years ago, on April 1, 2004, the Indian government launched Free Antiretroviral Therapy (ART) for Persons living with HIV (PLHIV).
- The Success free ART Therapy and subsequent steps under the NACP can potentially guide other public health programmes in the country.
AntiretroViral Drugs
- TDF- Tenofovir Disoproxil Fumarate,
- 3TC Lamivudine
- Efavirenz- EFV
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About ART Therapy: Antiretroviral Therapy (ART)
- ART Therapy is the treatment of people infected with human immunodeficiency virus (HIV) using anti-HIV drugs.
- The standard treatment consists of a combination of drugs (often called “highly active antiretroviral therapy” or HAART) that suppress HIV replication.
- Benefits:
- ART reduces mortality and morbidity rates among HIV-infected people and improves their quality of life.
- The benefits of ART also include the prevention of HIV transmission by suppressing HIV replication in persons living with the virus.
- This benefit of ART is also defined as “undetectable equal untransmittable” , or U=U.
Impact of Free ART Therapy
- Reduction in Prevalence: In 2023, the prevalence of HIV in 15-49 years has come down to 0.20 (confidence interval 0.17%-0.25%) and the burden of disease in terms of estimated PLHIV has been coming down to 2.4 million.
- India’s share in PLHIV globally had come down to 6.3% (from around 10% two decades ago).
- Status: As of the end of 2023, of all PLHIV, an estimated 82% knew their HIV status, 72% were on ART and 68% were virally suppressed.
- Decline in New Infections: The annual new HIV infections in India have declined by 48% against the global average of 31% (the baseline year of 2010).
- Decline in Mortalities: The annual AIDS-related mortalities have declined by 82% against the global average of 47% (the baseline year of 2010).
National AIDS Control Programme (NACP)
- The NACP, launched in 1992, is being implemented as a comprehensive programme for the prevention and control of HIV/ AIDS in India.
- Thirty-five years since then, NACP has evolved as one of the world’s largest programmes through
- five distinct phases.
- Currently, NACP-V (extension) is under implementation for 2021-2026.
NACP Phase-V:
- It is a Central Sector Scheme, fully funded by the Government of India, with an outlay of Rs 15471.94 crore.
- Aim: To reduce annual new HIV infections and AIDS-related mortalities by 80% by 2025-26 from the baseline value of 2010.
- It also aims to attain dual elimination of vertical transmission and elimination of HIV/AIDS-related stigma while promoting universal access to quality STI/RTI services to at-risk and vulnerable populations.
- Goal: In alignment with global targets agreed by the UNAIDS. NACP Phase-V calls for the attainment of ambitious targets of 95-95-95 by 2025.
- where 95% of all people living with HIV know their HIV status;
- 95% of all people diagnosed with HIV infection receive sustained antiretroviral therapy (ART), and
- 95% of all people receiving antiretroviral therapy achieve viral suppression by 2025.
Challenges in Achievements of Target:
- The delayed enrolment to the ART facilities.
- Non-adherence to ART Treatment and lack of follow-up.
- Sustained supply and availability of ART drugs.
- Low Private Sector Engagement
- Constant Training and Capacity Building of Staff
- Focus on strengthening integration with other programmes
- such as hepatitis, non-communicable diseases (diabetes and hypertension) and mental health.
- Focus on reducing preventable mortality.
About Human Immunodeficiency Virus (HIV)
- HIV (human immunodeficiency virus) is a Retrovirus virus that attacks the body’s immune system. If HIV is not treated, it can lead to AIDS (acquired immunodeficiency syndrome).
- Transmission: HIV is primarily spread through the exchange of certain bodily fluids such as blood, semen, vaginal fluids and breast milk.
- Affected the Immune System: HIV demolishes a particular type of White Blood Cells (WBCs) and the T-helper (CD4) cells, essential for the body’s ability to fight infections and diseases.
- Symptoms: Most people have flu-like symptoms within 2 to 4 weeks after infection. Symptoms may last for a few days or several weeks.
- Diagnosis: ELISA (Enzyme-Linked Immunosorbent Assay) TEST- It detects and measures antibodies in the blood.
- Treatment:
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- Anti-Retroviral Therapy
- Stem Cell Transplant
- Prevention includes safe sex, testing and counselling for HIV, voluntary medical male circumcision, among other things.
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