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Jardiance (Empagliflozin): A News Drug for Chronic Kidney Disease

February 16, 2024

Context: 

Recently, CDSCO has approved Boehringer Ingelheim’s anti-diabetic drug for the treatment of Chronic kidney disease in India.

Central Drugs Standard Control Organization (CDSCO) 

  • It is the National Regulatory Authority (NRA) of India regulates the quality, safety, and efficacy of drugs including vaccines & the medical devices industry.
  • Regulation: Drugs & Cosmetics Act 1940 & New Drugs and Clinical Trials Rules, 2019. 
  • Nodal Ministry: Ministry of Health & Family Welfare. 
  • Headed by: Drugs Controller General of India (DCGI)
  • Headquarters: New Delhi. 

What Is Chronic Kidney Disease (CKD)?

  • It means when kidneys are damaged and can’t filter blood the way they should. 
  • Main Risk factors: Diabetes, High Blood Pressure, Heart disease, and a family history of kidney failure.
  • CKD Burden in India: An estimated 33 million adults live with CKD in India.

About Jardiance Drug Efficacy

  • Reduce the risk of sustained decline in estimated glomerular filtration rate (eGFR) which is done to check how well the kidneys are filtering, and end-stage kidney disease.
  • Reduce Cardiovascular death (Earlier, it was approved only for the treatment of heart failure.)
  • Reduce Hospitalization of Adults with CKD.
Also Read: Casgevy And Lyfgenia: CRISPR-Based Gene Therapies

News Source: Live Mint

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