{"id":154549,"date":"2025-02-06T19:31:06","date_gmt":"2025-02-06T14:01:06","guid":{"rendered":"https:\/\/pwonlyias.com\/stage\/?post_type=current-affairs&#038;p=154549"},"modified":"2025-02-06T19:31:06","modified_gmt":"2025-02-06T14:01:06","slug":"garbh-ini-drishti-data-repository","status":"publish","type":"current-affairs","link":"https:\/\/pwonlyias.com\/stage\/current-affairs\/garbh-ini-drishti-data-repository","title":{"rendered":"GARBH-INi-DRISHTI Data Repository"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">The<\/span><b> Department of Biotechnology<\/b><span style=\"font-weight: 400;\"> has launched\u00a0 <\/span><b>its first Ferret Research Facility, the GARBH-INi-DRISHTI data<\/b><span style=\"font-weight: 400;\"> repository to advance maternal and child health research.<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">It also <\/span><b>signed a crucial technology transfer agreement.<\/b><\/li>\n<\/ul>\n<h2><span style=\"font-size: 18pt;\"><b>About GARBH-INi-DRISHTI Data Repository<\/b><\/span><\/h2>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Developed at:<\/b><span style=\"font-weight: 400;\"> Translational Health Science and Technology Institute (THSTI).<\/span>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"2\"><span style=\"font-weight: 400;\">THSTI is an autonomous institute of the Department of Biotechnology (DBT),\u00a0 located in Faridabad (Haryana).<\/span><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p style=\"text-align: center;\"><span class=\"vc_button\"><a href=\"https:\/\/www.pw.live\/batches\/upsc\/pw-only-ias?utm_source=seo+upsc+batch&#038;utm_medium=seo+upsc&#038;utm_campaign=seo&#038;utm_id=upsc\" target=\"_blank\" rel=\"noopener\">Enroll now for UPSC Online Classes<\/a><\/span><\/p>\n<div class=\"vc_table_green\"><\/p>\n<table style=\"width: 99.7979%;\">\n<tbody>\n<tr>\n<th style=\"width: 100%; border-style: solid; border-color: #000000; background-color: rgba(184, 165, 217, 0.53); text-align: left; vertical-align: middle;\">\n<h2><span style=\"font-size: 18pt; color: #000000;\"><b>About the Technology Transfer Agreement<\/b><\/span><\/h2>\n<ul>\n<li><span style=\"font-weight: 400; color: #000000;\">Technology Transfer Agreement signed with Sundyota Numandis Probioceuticals Pvt. Ltd.<\/span><\/li>\n<li><span style=\"color: #000000;\"><b>Objective:<\/b><span style=\"font-weight: 400;\"> To commercialize THSTI\u2019s innovative microbial consortium,<\/span><b> Lactobacillus crispatus<\/b><span style=\"font-weight: 400;\">, for women\u2019s health application.<\/span><\/span><\/li>\n<li><span style=\"color: #000000;\"><b>Potential Applications:<\/b><\/span><\/li>\n<li style=\"list-style-type: none;\">\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"2\"><span style=\"font-weight: 400; color: #000000;\">Nutraceuticals and probiotics for reproductive health.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"2\"><span style=\"color: #000000;\"><span style=\"font-weight: 400;\">Therapeutics for treating vaginal infections and <\/span><b>urinary tract infections (UTIs).<\/b><\/span><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<\/th>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><\/div>\n<ul>\n<li><b>Purpose<\/b><span style=\"font-weight: 400;\">: It will provide access to one of South Asia\u2019s largest pregnancy cohort datasets.<\/span><\/li>\n<li><b>Significance:<\/b><\/li>\n<li style=\"list-style-type: none;\">\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"2\"><span style=\"font-weight: 400;\">Contains clinical data, images, and biospecimens from over 12,000 pregnant women, newborns, and postpartum mothers.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"2\"><span style=\"font-weight: 400;\">Empowers global researchers to conduct studies on maternal and neonatal health.<\/span><\/li>\n<\/ul>\n<\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">It is part of GARBH-INi Program, a national initiative for maternal and child health research.<\/span><\/li>\n<\/ul>\n<h2><span style=\"font-size: 18pt;\"><b>About GARBH-INi Program<\/b><\/span><\/h2>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Objective<\/b><span style=\"font-weight: 400;\">: Enhances maternal and child health research and develops prediction tools for preterm birth.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Initiative by:<\/b><span style=\"font-weight: 400;\"> Department of Biotechnology, Union Ministry of Science and Technology.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Part of: <\/b><span style=\"font-weight: 400;\">Atal Jai Anusandhan Biotech Mission; <\/span><b>Undertaking Nationally Relevant Technology Innovation (UNaTI).<\/b><\/li>\n<\/ul>\n<h2><span style=\"font-size: 18pt;\"><b>About India\u2019s First Ferret Research Facility<\/b><\/span><\/h2>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">State-of-the-art biosafety laboratory designed for advanced biomedical research using ferrets.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Strengthens India\u2019s capacity for vaccine development, infectious disease research, and pandemic preparedness.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Facility Location:<\/b><span style=\"font-weight: 400;\"> THSTI, Faridabad, Haryana.<\/span><\/li>\n<\/ul>\n<h2><span style=\"font-size: 18pt;\"><b>Why Ferrets?<\/b><\/span><\/h2>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-154521 alignright\" src=\"https:\/\/pwonlyias.com\/stage\/wp-content\/uploads\/2024\/06\/64-67a4b4499351a.webp\" alt=\"GARBH-INi-DRISHTI Data Repository\" width=\"352\" height=\"212\" srcset=\"https:\/\/pwonlyias.com\/stage\/wp-content\/uploads\/2024\/06\/64-67a4b4499351a.webp 692w, https:\/\/pwonlyias.com\/stage\/wp-content\/uploads\/2024\/06\/64-67a4b4499351a-300x181.webp 300w\" sizes=\"(max-width: 352px) 100vw, 352px\" \/><\/p>\n<ul>\n<li><b>Ferrets (Mustela putorius furo):<\/b><\/li>\n<li style=\"list-style-type: none;\">\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"2\"><b>Small, carnivorous mammals<\/b><span style=\"font-weight: 400;\"> from the weasel family (Mustelidae).<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"2\"><span style=\"font-weight: 400;\">Domesticated for over<\/span><b> 2,500 years and commonly used in biomedical research.<\/b><\/li>\n<\/ul>\n<\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Ferrets are widely used in biomedical research, especially for:<\/span>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"2\"><span style=\"font-weight: 400;\">Respiratory diseases like influenza, COVID-19, and tuberculosis.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"2\"><span style=\"font-weight: 400;\">Vaccine and drug testing for emerging infectious diseases.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"2\"><span style=\"font-weight: 400;\">Neurological and gastrointestinal studies.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"2\"><span style=\"font-weight: 400;\">Reproductive health and genetic research.<\/span><\/li>\n<\/ul>\n<\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Reason for Preference<\/b><span style=\"font-weight: 400;\">: Their respiratory system closely resembles humans, making them ideal for studying airborne diseases.<\/span><\/li>\n<\/ul>\n<p style=\"text-align: center;\"><span class=\"vc_button\"><a href=\"https:\/\/store.pw.live\/govt-entrance-exams\/upsc-books\/upsc-textbooks?utm_source=SEO&#038;utm_medium=PW+Live&#038;utm_campaign=UPSC+Textbooks\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Check Out UPSC NCERT Textbooks From PW Store<\/span><\/a><\/span><\/p>\n<h2><span style=\"font-size: 18pt;\"><b>About Lactobacillus crispatus<\/b><\/span><\/h2>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Lactobacillus crispatus (L. crispatus)<\/b><span style=\"font-weight: 400;\">: A beneficial probiotic bacterium naturally present in the female reproductive and urinary tracts.<\/span>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"2\"><span style=\"font-weight: 400;\">Helps maintain a healthy vaginal microbiome by producing lactic acid, hydrogen peroxide (H\u2082O\u2082), and antimicrobial compounds.<\/span><\/li>\n<\/ul>\n<\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Lactobacillus crispatus &#038; THSTI\u2019s Research: <\/b><span style=\"font-weight: 400;\">THSTI isolated a <\/span><b>genetically defined strain of L. crispatus <\/b><span style=\"font-weight: 400;\">from Indian women enrolled in the GARBH-INi cohort.<\/span><\/li>\n<li><b>Essential for pregnant women as it:<\/b><\/li>\n<li style=\"list-style-type: none;\">\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"2\"><span style=\"font-weight: 400;\">Reduces the risk of preterm birth.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"2\"><span style=\"font-weight: 400;\">Prevents infections linked to infertility and pregnancy complications.<\/span><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p><b><i>Ready to boost your UPSC 2025 preparation?<\/i><\/b> <a href=\"https:\/\/www.pw.live\/batches\/upsc?utm_source=seo+upsc+batch&#038;utm_medium=seo+upsc&#038;utm_campaign=seo&#038;utm_id=upsc\" target=\"_blank\" rel=\"noopener\"><b><i>Join PW&#8217;s UPSC online courses<\/i><\/b><\/a><b><i> today!<\/i><\/b><\/p>\n<div class=\"vc_table_green\"><\/p>\n<table style=\"width: 99.6375%;\">\n<tbody>\n<tr>\n<td style=\"width: 111.19%; 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