Scientists have created the first-ever Asian rice pangenome, encompassing genetic data from 144 wild and cultivated rice varieties.
What is a Pangenome?
- A pangenome is a comprehensive genomic resource that includes both core genes shared by all individuals and unique genes found in some individuals of a species.
- It offers a more complete picture of genetic variation than a traditional reference genome.
Significance for Rice Genetics and Food Security
- Global Importance: Rice (Oryza sativa L.) is a staple food for two-thirds of the global population and a critical crop in Asia.
- Genetic Benefits: Understanding genetic diversity helps improve disease tolerance, climate resilience, and nutritional quality of rice.
- Domestication Link: The study strengthens knowledge of rice domestication, linking modern rice to wild progenitor O. rufipogon, particularly the Or-IIIa group, ancestor of japonica rice.
- Stress Adaptation: The pangenome offers genetic resources to enhance rice’s adaptation to environmental stress and regenerative potential.
Differences between a Pangenome and a Reference Genome
Feature |
Reference Genome |
Pangenome |
Definition |
Genome of a single representative variety |
Combined genomic data from multiple varieties |
Gene Coverage |
Includes only the genes present in one variety |
Includes both core (shared) and unique genes from many varieties |
Core Genes Identified |
Not specifically categorized |
28,907 core genes shared among all studied varieties |
Unique/Wild-Specific Genes |
Typically not included |
Includes 13,728 wild-rice-specific genes |
Genetic Material Coverage |
Limited to one genome |
Contains 3.87 billion base pairs of novel sequences not in the reference genome |
Genetic Diversity Representation |
Low |
High as it captures broader genetic variation |
Utility |
Basic genetic reference |
Enables identification of novel traits and improved trait mapping |
Use in Breeding Programs |
Limited applicability |
High potential for developing stress-tolerant and high-yield varieties |
Applications in Crop Resilience and Breeding
- The pangenome enables scientists to:
- Develop new rice cultivars with better resistance to drought and diseases
- Transfer beneficial traits from wild rice to cultivated rice
- Address climate change impacts, such as yield loss and increased arsenic uptake
- Using ‘PacBio high-fidelity’(HiFi) sequencing technology and computational methods, the analysis revealed 3.87 billion base pairs of novel genetic sequences.
- These Genome data can guide precision breeding for yield enhancement, stress tolerance, and climate adaptation.
Status of India’s Rice Production and Research
- India produced a record 220 million tonnes of rice in 2024–25 with an average yield of 4.2 tonnes/ha.
- In 2024, the Indian Council of Agricultural Research (ICAR) announced genome-edited varieties like Samba Mahsuri and MTU 1010 with improved drought resistance and higher yields.
- India’s rising temperatures (0.7°C since 1901; 2024 was the hottest year on record) make such research critical for national food security.
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