Photoacoustic Technology for Glucose Monitoring

PWOnlyIAS

March 22, 2025

Photoacoustic Technology for Glucose Monitoring

Researchers at the Indian Institute of Science (IISc) have developed a groundbreaking technique that offers a painless alternative to traditional blood glucose testing. 

  • This new technique, called photoacoustic sensing, eliminates the need for frequent needle pricks, offering a more comfortable and safer alternative for diabetic patients.  

How Photoacoustic Sensing Works?

  • Photoacoustic sensing relies on the interaction between light and biological tissue:  
    • A laser beam is directed at the tissue, causing it to absorb light and heat up slightly (less than 1°C).  
    • This heating causes the tissue to expand and contract, generating ultrasonic sound waves.  
    • Since different molecules absorb light differently, the sound waves carry unique “fingerprints” of the substances in the tissue.
  • The photoacoustic effect is the generation of sound waves (ultrasound) following the absorption of light (typically a laser pulse) by a material. 
  • This effect occurs when a material absorbs light energy, leading to rapid thermal expansion and creating pressure waves (sound waves) that can be detected with acoustic sensors.

About Photoacoustic Effect

Discovery and History

  • Discovered by Alexander Graham Bell in 1880 while experimenting with modulated sunlight and its effect on different materials.
  • Initially used for gas analysis, it later found applications in imaging and sensing technologies.

How Does It Work?

  • Light Absorption – A pulsed or modulated light source (usually a laser) irradiates a material.
  • Thermal Expansion – The absorbed energy causes localized heating, leading to rapid thermal expansion.
  • Ultrasound Generation – The expansion generates acoustic (ultrasonic) waves, which propagate through the material.
  • Detection – Acoustic waves are detected using microphones (for gases) or ultrasound transducers (for solids and biological tissues).
  • Analysis – The detected signals are analyzed to determine material properties, composition, or structure.

Applications of the Photoacoustic Effect

  • Biomedical Imaging – Photoacoustic tomography (PAT) and microscopy (PAM) for imaging blood vessels, tumors, and tissues.
  • Gas Sensing – Used in environmental monitoring to detect pollutants like CO2, methane, and ammonia.
  • Material Characterization – Examines properties of nanomaterials, semiconductors, and coatings.

Future Implications of the discovery

  • This non-invasive technique could revolutionize glucose monitoring, offering greater convenience and reduced health risks for diabetic patients. 
  • While the exact reason for the acoustic signal change is still being studied, the strong correlation between glucose levels and sound intensity opens new doors for painless medical diagnostics.

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Quick Revise Now !
UDAAN PRELIMS WALLAH
Comprehensive coverage with a concise format
Integration of PYQ within the booklet
Designed as per recent trends of Prelims questions
हिंदी में भी उपलब्ध

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