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India has introduced the world’s first genome-edited rice varieties—DRR Dhan 100 Kamla and Pusa DST Rice 1—using technologies like CRISPR-Cas9 without adding foreign genes. These crops offer higher yield, better drought and salt tolerance, and improved water efficiency, making them crucial for climate-resilient agriculture and food security.
Among the UPSC Science and Technology most important topics, the recent release of the world’s first two genome-edited rice varieties stands out as a significant milestone in India’s agricultural innovation. Developed by the Indian Council of Agricultural Research (ICAR), this advancement aims to bolster food security and promote sustainable farming practices.
These varieties—DRR Dhan 100 Kamla and Pusa DST Rice 1—are distinct from genetically modified (GM) crops because they do not involve the introduction of foreign genes, focusing instead on precise gene editing through technologies like CRISPR-Cas9 and SDN1
India has become the first country in the world to release two genome-edited rice varieties. These varieties were released by the ICAR (Indian Council of Agricultural Research) in May 2025. It is important to note that these are genome-edited, not transgenic or genetically modified (GM) crops. Rice is a vital part of the diet and a significant export commodity for India.
The two newly released genome-edited rice varieties are:
The DRR Dhan 100 Kamla variety was developed using SDN1 (Site-Directed Nuclease 1) technology. This technology employs a “molecular scissor” capable of cutting DNA or a specific gene This variety was developed by genome editing the already popular Samba Mashuri variety
.Key Features of DRR Dhan 100 Kamla:
(Memory Tip: When the term ‘nuclease’ appears, it signifies a ‘molecular scissor’).
The Pusa DST Rice 1 variety is designated for Drought and Salt Tolerant (DST) characteristics. This variety was developed using CRISPR-Cas9 technology.
Key Features of Pusa DST Rice 1:
The development of these varieties is important for addressing the harmful impacts of climate change, which affects rain patterns and agricultural conditions. These climate-resilient crops aim to ensure food and nutrition security.
Summary of Key Benefits:
The two primary technologies used for these genome-edited rice varieties are:
The distinction between genome-edited (non-transgenic) and transgenic crops is fundamental.
| Genome-Edited (Non-Transgenic) Vs Transgenic Crops | ||
| Feature | Genome-Edited (Non-Transgenic) | Transgenic (Genetically Modified/GM)
|
| Gene Action | Removal of gene (DNA is “snipped out”). No gene addition. | Insertion of foreign gene (from different species). Gene addition. |
| Risk Profile | Lower risk to environment, human, or cattle health. | Higher risk to environment, human health, and the entire agriculture system. |
| Regulation | Regulatory exemptions (e.g., Indian DBT exempts SDN1 & SDN2 crops from GMO rules 2022). Shorter safety assessment, easier commercial rollout. | Very stringent rules and regulations (e.g., GMO rules). Requires decades-long safety assessments before commercial approval. |
| Examples | DRR Dhan 100 Kamla, Pusa DST Rice 1 | Bt cotton (only commercially grown transgenic crop in India, non-edible). GM mustard is in legal trouble. |
The development of these genome-edited rice varieties is relevant for India’s strategic goals, aligning with the concept of a “Second Green Revolution.”
Goals of the Second Green Revolution:
This strategy aims to produce 10 million tons more rice while utilizing 5 million hectares less land. This highlights the efficiency and sustainable potential of these new crop varieties.
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Genome-edited rice varieties involve precise changes to a crop's existing genes without introducing foreign DNA. In contrast, genetically modified (GM) crops involve inserting genes from a different species. The newly released Indian varieties are genome-edited, not transgenic or GM.
India has released two genome-edited rice varieties: DRR Dhan 100 Kamla and Pusa DST Rice 1.
DRR Dhan 100 Kamla offers an approximately 19-20% increase in yield, matures 15-20 days earlier, exhibits moderate drought resistance, and retains good grain quality.
Pusa DST Rice 1 is designed for Drought and Salt Tolerant (DST) characteristics. It requires less water, is highly tolerant to drought and salinity, and can lead to up to 30% higher yield in challenging soil conditions.
The primary technologies used are CRISPR-Cas9 and SDN1 (Site-Directed Nuclease 1). Both function as "molecular scissors" to precisely edit specific genes in the rice genome.
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