Pig’s Kidney Transplanted into Humans

August 19, 2023

GS Paper III Science and Technology

Context:

American surgeons have reported successful functioning of a pig kidney transplanted into a brain-dead human patient’s body, with the organ performing effectively for over a month.

More about the news:

Pigs are easier to genetically modify. They also breed better with large litter, grow faster, and are less likely to transmit infections. The size of their organs is also similar to humans.
The transplant involved using a pig kidney that had been genetically modified to disable a gene responsible for producing the sugar molecule known as Alpha-gal.
- Alpha-gal is a molecule that is typically absent in humans, but its presence can trigger a severe immune reaction in human bodies.
If found compatible in the long run, this process of Xenotransplantation, or transplanting organs between different species, could help provide an alternative and additional supply of organs for people facing life-threatening diseases.

News Source: TOI

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