Smart insulin

19 Oct 2024

Scientists have developed a “smart” insulin NNC2215  that can adjust in real time to changes in blood sugar levels, a long-sought “holy grail” in diabetes treatment, according to research published in the journal Nature.

About Smart Insulin (NNC2215)

  • Smart insulin is a drug designed to circulate in the body and turn on when it’s needed and off when it’s not.
  • NNC2215 is a smart insulin that consists of two key components:
    • A ring-shaped structure and a  glucoside molecule (similar in shape to glucose).

Smart insulin

How NNC2215 Works? 

  • When blood sugar levels are low, the glucoside binds to the ring, keeping the insulin inactive to prevent further lowering of blood sugar.
  • As blood glucose levels rise, glucose replaces the glucoside, causing the insulin to change its shape and become active, helping to lower blood sugar to safer levels.

Enroll now for UPSC Online Course

About Diabetes

  • Diabetes is a non-communicable disease (NCD) that occurs either when the pancreas does not produce enough insulin or when the body cannot effectively use the insulin it produces. 
    • Insulin is the hormone responsible for regulating blood sugar (glucose).

Types of Diabetes

Smart insulin

  • Type 1 Diabetes: The immune system destroys insulin-producing beta cells in the pancreas and the body produces very little or no insulin.
    • Commonly diagnosed in children and young people, hence called Juvenile Diabetes.
  • Type 2 Diabetes: Results from the body’s ineffective use of insulin it produces.
    • It is often associated with lifestyle factors and is more common in adults.
  • Gestational Diabetes: Occurs in women during pregnancy when the body becomes less sensitive to insulin.
    • Typically temporary but can increase the risk of developing type 2 diabetes later.

Impacts of Diabetes: Diabetes can affect five major organs ie Kidneys, Heart, Blood vessels, Nervous system and Eyes (retina).

Archive Calendar

Mon Tue Wed Thu Fri Sat Sun
 123
45678910
11121314151617
18192021222324
25262728293031

Need help preparing for UPSC or State PSCs?

Connect with our experts to get free counselling & start preparing

Know about Physics Wallah

Physics Wallah is an Indian online education platform, that provides accessible & comprehensive learning experiences to students of classes 6 to 12 and those preparing for JEE and NEET exams. We also provide extensive NCERT solutions, sample papers, NEET, JEE Mains, BITSAT previous year papers, which makes us a one-stop solution for all resources. Physics Wallah also caters to over 3.5 million registered students and over 78 lakh+ Youtube subscribers with 4.8 rating on its app.

We Stand Out because

We successfully provide students with intensive courses by India's qualified & experienced faculties. PW strives to make the learning experience comprehensive and accessible for students of all sections of society. We believe in empowering every single student who couldn't dream of a good career in engineering and medical field earlier.

Our Key Focus Areas

Physics Wallah’s main focus is to create accessible learning experiences for students all over India. With courses like Lakshya, Udaan, Arjuna & many others, we have been able to provide a ready solution for lakhs of aspirants. From providing Chemistry, Maths, Physics formulae to giving e-books of eminent authors, PW aims to provide reliable solutions for student prep.

What Makes Us Different

Physics Wallah strives to develop a comprehensive pedagogical structure for students, where they get a state-of-the-art learning experience with study material and resources. Apart from catering students preparing for JEE Mains and NEET, PW also provides study material for each state board like Uttar Pradesh, Bihar, and others.

Aiming for UPSC?

Download Our App

# #
Quick Revise Now !
AVAILABLE FOR DOWNLOAD SOON
UDAAN PRELIMS WALLAH
Comprehensive coverage with a concise format
Integration of PYQ within the booklet
Designed as per recent trends of Prelims questions
हिंदी में भी उपलब्ध
Quick Revise Now !
UDAAN PRELIMS WALLAH
Comprehensive coverage with a concise format
Integration of PYQ within the booklet
Designed as per recent trends of Prelims questions
हिंदी में भी उपलब्ध

<div class="new-fform">






    </div>

    Subscribe our Newsletter
    Sign up now for our exclusive newsletter and be the first to know about our latest Initiatives, Quality Content, and much more.
    *Promise! We won't spam you.
    Yes! I want to Subscribe.