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New Class of Antibiotic Against a Drug-Resistant Bacterium

January 6, 2024

GS Paper III Science and Technology

Context: Researchers have identified a new class of antibiotics with the potential to tackle a drug-resistant bacterium, Acinetobacter baumannii.

Zosurabalpin: New Class of Antibiotic for Drug-Resistant Bacterium

Zosurabalpin was found to be effective against CRAB (carbapenem-resistant Acinetobacter baumannii)-induced pneumonia and sepsis in mouse models.
Trials: The antibiotic has been evaluated in two phase I clinical trials.

About Acinetobacter baumannii

It is a bacterial pathogen primarily associated with hospital-acquired infections.
It is commonly associated with aquatic environments and colonizes the skin as well as the respiratory and oropharynx secretions of infected individuals.

What is Antimicrobial Resistance (AMR)?

Antimicrobial Drug Resistance or Antimicrobial Resistance (AMR) occurs when bacteria, viruses, fungi and parasites no longer respond to antimicrobial medicines.
Impact: Infections become difficult or impossible to treat, increasing the risk of disease spread, severe illness, disability and death.
Reason: AMR is a natural process that happens over time through genetic changes in pathogens.

To Read More: Antimicrobial Resistance (AMR)

News Source: The Hindu

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