Bharat Biotech in collaboration with the Indian Council for Agricultural Research(ICAR) has developed the world’s first Biolumpivaxin vaccine for the Lumpy Skin Disease (LSD).
- The vaccine is developed by Biovet which is a Bharat Biotech group firm.
- The vaccine has recently received approval from the Central Drug Standards Control Organization (CDSCO), marking a significant milestone in India’s veterinary healthcare sector.
Key Features of Biolumpivaxin
- Global First: Biolumpivaxin is the world’s first DIVA (Differentiating Infected from Vaccinated Animals) marker vaccine for Lumpy Skin Disease.
- DIVA Technology: Enables differentiation between naturally infected and vaccinated animals, aiding in disease surveillance and control programs.
- High Safety and Efficacy: The vaccine has been rigorously tested for quality, safety, and effectiveness.
- Single-Dose Regimen: Administered once a year to cattle and buffaloes above 3 months of age.
- Vaccine Strain: Developed using the LSD virus/Ranchi/2019 strain from ICAR-NRCE, Hisar.
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Lumpy Skin Disease (LSD)
- Lumpy Skin Disease (LSD) is a highly contagious viral disease affecting cattle and buffaloes.
- It is caused by the Lumpy Skin Disease Virus (LSDV), a member of the Poxviridae family.
- The first reported outbreak of LSD occurred in Zambia in 1929.
- The LSD spreads through blood-sucking vectors like ticks and mites like houseflies, mosquitoes, etc. It also spreads through contaminated water, fodder and feed.
- The disease leads to severe economic losses in the dairy and livestock industry due to reduced milk production, infertility, and mortality.
![Biolumpivaxin](https://pwonlyias.com/wp-content/uploads/2025/02/11.4.webp)
Differentiating Infected from Vaccinated Animals
- DIVA vaccines are specially designed vaccines that allow for the differentiation between naturally infected and vaccinated animals.
- They are widely used in livestock disease control programs to prevent disease outbreaks while enabling disease surveillance and eradication efforts.
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Advantages of DIVA Vaccines |
Disadvantages of DIVA Vaccines |
- Identify infected animals: DIVA vaccines can help identify infected animals so that special restrictions can be relaxed for vaccinated animals.
- Monitor vaccine efficacy: DIVA vaccines can be used to monitor the transmission of wild-type viruses in vaccinated populations.
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- Less effective: DIVA vaccines may not be as effective as conventional vaccines.
- Special diagnostic tests: Special diagnostic tests are required to identify infected animals. These tests may not be as sensitive as conventional tests.
- Development: Developing DIVA vaccines can be challenging.
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